BioMark Partners with Alberta Machine Intelligence Institute to Amplify Clinical Diagnostic Decision Making

Vancouver, British Columbia – (April 25, 2018) – BioMark Diagnostics Inc. (“BioMark”) (CSE: BUX, FSE: 20B, OTCMKTS: BMKDF) is pleased to announce that it has penned a deal with the Alberta Machine Intelligence Institute (Amii) led by Dr. Osmar Zaïane of the University of Alberta’s Department of Computing Science and his team to assess and employ machine intelligence to augment BioMark’s breakthrough biological molecular diagnostics for lung cancer that leverages the power of metabolomics.

BioMark, over the past few months, has been actively working with the team at Amii to find optimal methodologies to increase the prediction and accuracy of its assays. President and CEO Rashid Bux says, “We realize the importance of machine and deep learning in the future of healthcare delivery. There is immense impact in patient care outcome and faster diagnostic utility for clinicians through incorporating machine intelligence capabilities. Our initial objective is to increase the performance and prediction of our lung cancer diagnostic assays by reducing data bias to establish consistency. Eventually, we aim to establish models that have the ability to predict trends in our network, which will amplify decision making for clinicians. Once completed, BioMark intends to incorporate this as an application-driven breakthrough embedded seamlessly onto our technology platform. BioMark is delighted to work with Dr. Zaïane and Amii from University of Alberta who are creating game changing applications using machine learning and artificial intelligence.”

 

About BioMark Diagnostics Inc.

BioMark is developing proprietary, non-invasive, and accurate cancer diagnostic solutions which can help detect, monitor and assess treatment for cancer early and cost effectively. The technology can also be used for measuring response to treatment and potentially for serial monitoring for cancer survivors.

 

About Alberta Machine Intelligence Institute (Amii)

The Alberta Machine Intelligence Institute (Amii) is a world-leading research group at the University of Alberta in Edmonton specializing in machine intelligence. One of three hubs in Canada’s Pan-Canadian AI Strategy, Amii conducts advanced research and development in the many subfields of machine learning and artificial intelligence. Amii researchers collaborate with a variety of organizations to help push the bounds of scientific knowledge and develop innovative, adaptive solutions for businesses in Alberta and beyond. Learn more at www.amii.ca

Press Release – BioMark Partners with Alberta Machine Intelligence Institute to Amplify Clinical Diagnostic Decision Making

BioMark Diagnostics – Sponsored Project Receives NSERC Engage Grant

Vancouver, British Columbia – (February 27th, 2018)–BioMark Diagnostics Inc. (CSE: BUX, FSE: 20B, OTCMKTS: BMKDF) announces the award of a grant from the Natural Sciences and Engineering Research Council of Canada (NSERC) to partner with Donald Miller, Ph.D., Professor, Department of  Pharmacology and Therapeutics  at the University of Manitoba, to fabricate new nanomaterial and focus on evaluation of these new nanomaterial for knocking down SSAT1 expression in various cells .The up regulation of  SSAT enzyme  has been clinically demonstrated by BioMark and others to be highly elevated in  lung, breast, prostate and brain cancers.

President and CEO, Rashid Ahmed explains, “We are delighted to be working with Dr. Miller and his team at the University of Manitoba to help BioMark assess the potential of designing new nanomaterials that can be used to target the metabolic pathway associated in the up-regulation of SSAT for various cancers.   Dr. Miller has domain expertise and over 20 years of experience in fabricating, evaluating and developing polymer and metal oxide based nanoparticle compounds and delivery systems for various applications including the brain. He will direct the project and supervise the design of these novel nanomaterial candidates which provide more options to deliver a knock down SSAT compound enabling a potential better treatment associated with various cancers.”

Rashid says, “BioMark is grateful to the Canadian government for awarding it yet another grant that supports work to advance this important technology toward commercialization.”

Press Release – BioMark Diagnostics-Sponsored Project Receives NSERC Engage Grant

BioMark’s Health Canada Submission Update

Vancouver, British Columbia – (February 21st, 2018) – BioMark Diagnostics Inc. (“BioMark”) (CSE: BUX, FSE: 20B, OTCMKTS: BMKDF) is pleased to provide an update on its Health Canada submission progress following data analysis on its clinical trial activities.

Listed below are new accomplishments over the past 2 weeks:

  1.  BioMark’s regulatory team at St. Boniface Hospital Research Centre and the assigned biostatistician have completed detailed data analysis and tabulation on clinical trials based in Canada and Bangladesh.
  2. A comprehensive medical follow up report of the outliers in both in Canada and Bangladesh has been reviewed by Dr. Andrew Maksymiuk, the Principal Investigator at CancerCare Manitoba along with our regulatory team members from St. Boniface Hospital Research Centre. Initial assessment report of the outliers demonstrates BioMark SSAT1 technology can provide physicians an economical diagnostic tool to effectively pre-screen patients for either more expensive CT screening or more invasive biopsy procedure. (Outliers are subjects who were considered healthy but exhibited higher than expected Acetyl Amantadine concentrations). An ongoing follow up will serve as part of our surveillance and strengthen the clinical applicability of our data.
  3. Compilation of the package to be filed with Health Canada has begun and a team has been assembled to accelerate the submission.

Next Steps
News will be released as soon as the submission package is completed in the next couple of weeks.

News Release – BIOMARK’s Health Canada Submission Update

Further Progress in BIOMARK’s Clinical Trial and Regulatory Review

Vancouver, British Columbia – (January 3rd, 2018) – BioMark Diagnostics Inc. (“BioMark”) (CSE: BUX, FSE: 20B, OTCMKTS: BMKDF) is pleased to provide further progress on its clinical trial activities as previously reported on November 1st, 2017.

New accomplishments over the past few weeks are listed below.

  1.  Samples from the outlier cohort have been received at Biopharmaceutical Research Inc. (BRI) in Vancouver where they are being analyzed under Good Laboratory Practice utilizing Health Canada Investigational Testing Authorization standards granted to BioMark under application # 229838. (Outliers are subjects who were considered healthy, but exhibited higher than expected Acetyl Amantadine concentrations). BRI received the customized reference standard material from United States that is used to calibrate the equipment following a delay in manufacturing. BRI anticipates that it will now require about 2 weeks to complete analysis and data tabulation for the biostatisticians in Manitoba to review.
  2. A comprehensive medical follow-up report of the outliers in both in Canada and Bangladesh is being reviewed by Dr. Andrew Maksymuik, the Principal Investigator at CancerCare Manitoba along with our scientists and regulatory team members from St. Boniface Hospital Research Center. A good assessment report of the outliers would demonstrate that BioMark’s SSAT1 technology can provide physicians a definitive diagnostic tool to cost effectively prescreen patients for either more expensive CT screening or more invasive biopsy procedure. In addition, the medical follow-up report will be useful as part of the submission package to be filed with Health Canada.

Next Steps
BioMark continues to work with all the parties to ensure that all the data is received and tabulated for a comprehensive submission package to Health Canada as soon as possible after the completion of the new incoming data analysis and reports. The regulatory group has begun to compile elements of the submission package to Health Canada.

News Release – Further Progress on BIOMARK’s Clinical Trial and Regulatory Review