BIOMARK TO OPEN A DIAGNOSTIC LABORATORY IN QUÉBEC

Vancouver, British Columbia – (April 29, 2021) – BioMark Diagnostics Inc. (“BioMark”) (CSE: BUX) (FSE: 20B) (OTCMKTS: BMKDF) is pleased to announce today that its wholly-owned subsidiary BioMark Diagnostic Solutions Inc. (“BDS”) will be operating a diagnostic laboratory in Quebec, Canada, which will primarily serve to advance the clinical validation of its proprietary liquid biopsy platform for early lung cancer detection, monitoring and predicting response to treatment.

 

The company’s aim is to obtain regulatory approval and clinical laboratory licenses to be fully operational in early 2022 and start offering its metabolomics biomarker panel for early lung cancer detection to physicians initially across the Province of Quebec. BioMark’s technology alliance with Quebec-based Phytronix Technologies Inc. enhanced its technical capabilities with extensive automated sample preparation and mass spectrometry assay development that prompted the opening of its own diagnostic laboratory.

 

“This move to Quebec City represents the successful accomplishment of our strategic plan to bring the company to its pre-commercialization stage. The fact that BioMark is spearheading the commercialization of its assay from its own clinical laboratory in Quebec, Canada and later across North America will certainly create more value for our shareholders.” said Rashid Bux, CEO of BioMark.

 

In conjunction with expanding our infrastructure in Quebec, BioMark is also pleased to report that Dr. Jean-François (Jeff) Haince will be leading our laboratory operation as General Manager for BDS. Rashid Ahmed, President and CEO, says, “We are delighted that Jeff decided to join our management team and lead our operation as he has been instrumental in setting up our lab infrastructure and capacity. Jeff possesses an excellent understanding of the whole value chain and regulatory landscape in the molecular diagnostic field and has played a vital role in the commercialization of two early cancer detection molecular diagnostics. Jeff’s experience is poised to propel our transition from being research and development focused to a commercialization driven entity”.

 

About Phytronix Technologies Inc.

 

Phytronix Technologies Inc. is a privately-owned company based in Québec City, Canada, and was founded in 2000. Phytronix invented and patented the Laser Diode Thermal Desorption (LDTD) technology for mass spectrometry. The company introduced the Luxon Ion Source®, which is the second-generation apparatus based on the patented-LDTD® technology and currently the fastest technology for mass spectrometry. This innovative technology enables ultra-high-speed analysis in less than 4 seconds per sample. The company will provide the optimized internal standards that are necessary for use in clinical settings, along with technical expertise required with high-throughput mass spectrometry.

Press Release – BIOMARK TO OPEN A DIAGNOSTIC LABORATORY IN QUÉBEC

BIOMARK ANNOUNCES EXERCISE OF WARRANTS AND GAIN DTC ELIGIBILITY FOR ITS COMMON SHARES

Vancouver, British Columbia – (April 21, 2021) – BioMark Diagnostics Inc. (“BioMark”) (CSE: BUX) (FSE: 20B) (OTCMKTS: BMKDF) is pleased to announce today the agreement by several long-time strategic accredited investors and insiders to exercise approximately 2,000,000 warrants issued in connection with the Company’s private placement of units completed in April 2019, with the warrant exercise price of $0.20 per share.  All the warrants were exercised before the warranty maturity date of April 16, 2021. The gross proceeds to the company from the exercise of the warrants are expected to be approximately $400,000.00.

 

BioMark intends to use the net proceeds from the warrant exercise to fund ongoing clinical validation of its liquid biopsy platform and working capital for its clinical lab facilities in Québec as well as for other general corporate purposes.

 

“The infusion of equity indicates a strong appreciation from investors in BioMark’s fundamentals that will continue this momentum through the end of the year. This strengthening of the balance sheet is one more piece in our plan to accelerate the pre-commercialization of our early detection and screening diagnostics assays for lung cancers” said Rashid Bux, CEO of BioMark.

 

In addition, BioMark also would like to announce that its common shares will now be eligible for electronic clearing and settlement through the Depository Trust Company (“DTC”). DTC is a subsidiary of the Depository Trust & Clearing Corporation, a US company that manages the electronic clearing and settlement of publicly traded companies. Through an electronic method of clearing securities, DTC eligibility simplifies the process of trading and transferring the Company’s common shares between brokerages in the United States.

 

BioMark’s common shares are now fully DTC eligible and will continue to trade under the ticker symbol “BMKDF” on the OTC market. “We are excited with obtaining DTC eligibility, as it represents an important step forward in broadening our shareholder base and building a strong presence for our company within the US capital markets sphere”, said Rashid Bux, CEO of BioMark.

Press Release – BIOMARK ANNOUNCES EXERCISE OF WARRANTS AND GAIN DTC ELIGIBILITY FOR ITS COMMON SHARES

BIOMARK’S COLLABORATOR RECEIVES FUNDING TO VALIDATE ITS BIOMARKER PANEL FOR THE EARLY DETECTION OF LUNG CANCER

Vancouver, British Columbia – (March 16, 2021) – BioMark Diagnostics Inc. (“BioMark”) (CSE: BUX) (FSE: 20B) (OTCMKTS: BMKDF) is pleased to announce today that its sponsored research collaboration with The Metabolomics Innovation Centre (TMIC) was successful in receiving funding from the Novel Technology Application in Cancer Prevention and Early Detection Spark Grants competition. This comes after the organizers of the competition, the Canadian Cancer Society/Canadian Institutes of Health Research – Institute of Cancer Research, and Brain Canada Foundation, evaluated the full proposal for its relevance to funding opportunities in the prevention and early detection of cancer. The funding application is entitled “A novel rapid, liquid biopsy early-stage lung cancer diagnostic test”. The grant was for $150,000.

 

The study is being led by Professor David Wishart and his team at The Metabolomics Innovation Centre from the Departments of Biological Sciences and Computing Science at the University of Alberta. The funding will be used to validate BioMark’s liquid biopsy platform and proprietary biomarker panel for the detection of early-stage lung cancer in over 1200 patients. Our team, which consists of leaders in oncology, lung cancer, mass spectrometry and clinical translation will work together to ensure the successful translation, implementation, and commercialization of this metabolomics assay. Upon completion of this project, we expect to have: 1) a validated biomarker panel for the detection of early-stage lung cancer; 2) a laboratory-developed test that is compatible and easily integrated on mass spectrometry platforms already routinely used in clinical labs and 3) a well-developed plan for translation and implementation of the test using a proprietary system in an accredited lab in Quebec and later across Canada.

 

“We are delighted to continue our collaboration with Dr. Wishart and his team at TMIC. Over the past 4 years we have worked hard to establish metabolite biomarkers that are specific to lung cancer in plasma samples and now we begin the final stretch in validating our test toward commercialization across Canada. A simpler, cheaper and more accurate test for early detection of lung cancer would benefit patients by providing improved outcome to high-risk patients. Such a test will also have the potential to disrupt the management of patient at higher risk due to smoking and other environmental exposures, leading to better screening modalities and reduced healthcare burden globally,” Mr. Bux added.

 

About Sparks Grant.

 

BioMark would like to thank The Canadian Cancer Society (CCS), the Canadian Institutes of Health Research – Institute of Cancer Research (CIHR-ICR), and Brain Canada Foundation for their generous financial support for Spark Grants on the Application of Disruptive Technologies in Cancer Prevention and Early Detection of the Canadian Cancer Society and the Canadian Institutes of Health Research-Institute for Cancer Research and Brain Canada Foundation (CCS grant # 707073/CIHR-IRSC grant # 0590008438). Both TMIC and BioMark will acknowledge all the supporting agencies in publications or events related to the use of the funds.

 

 

About TMIC

 

The Metabolomics Innovation Centre (TMIC) is a nationally funded network that offers a unique combination of infrastructure and expertise to perform a wide range of cutting-edge metabolomic studies for clinical trials research, biomedical studies, bioproducts studies, nutrient profiling and environmental testing. Network scientists include Dr. Liang Li (University of Alberta), Dr. David Wishart (University of Alberta), Dr. Christoph Borchers (McGill University), Dr. James Harynuk (University of Alberta), Dr. Michael Overduin (University of Alberta), Dr. David Goodlett (University of Victoria), Dr. Philip Britz-McKibbin (McMaster University) and Dr. Ian Lewis (University of Calgary).

TMIC has access to more than $26 million in state-of-the-art metabolomics infrastructure. It is supported by a team of lab managers, NMR spectroscopists, mass spectrometrists, chemists, computer scientists, statisticians and bioinformaticians. TMIC is capable of identifying and quantifying up to 2000 different chemicals from certain biological samples. This is approximately 5X more comprehensive than any other service currently available.

Press Release – BIOMARK’S COLLABORATOR RECEIVES FUNDING TO VALIDATE ITS BIOMARKER PANEL FOR THE EARLY DETECTION OF LUNG CANCER

BIOMARK GRANTS OPTIONS

Vancouver, British Columbia – (March 2, 2021) – BioMark Diagnostics Inc. (“BioMark”) (CSE: BUX) (FSE: 20B) (OTCMKTS: BMKDF) is pleased to announce that it has granted 2,100,000 incentive stock options under the Company’s Stock Option Plan (“Option Plan”) to third-party consultants to support market communication and corporate strategy as it advances its commercialization efforts. Each option is exercisable into one common share at a price of $0.25 per share and will vest immediately. The options will expire two years from the date of grant. All other terms and conditions of options are in accordance with the terms of the Company’s Stock Option Plan.

In addition, BioMark has cancelled 100,000 options previously issued to consultants.

Press Release – BioMark Grants Options