Vancouver, British Columbia – (November 21st, 2019) – BioMark Diagnostics Inc. (“BioMark”) (CSE: BUX) (FSE: 20B) (OTCMKTS: BMKDF) is pleased to announce a non-brokered Private Placement (the “Offering”). The Offering will be for up to 1,666,667 Units at a price of $0.30 to raise gross proceeds of up to $500,000.


Each Unit is composed of one common share (a “Share”) of the Company and one-half Share purchase warrant (a “Warrant”). Each whole Warrant shall entitle the holder to acquire one Share at a price of $0.45 per Share for a period of two years after the date of issuance. Finder’s fees may be payable. The private placement and finder’s fees are subject to regulatory approval.


The proceeds of the Offering will be used for new product development activities, sourcing clinical samples, new patent submission costs and general working capital. The securities in the private placement will be subject to a holding period of four months from the closing date of the private placement. Certain Insiders, Directors and Officers may subscribe for a portion of this placement. Closing of the private placement is subject to the Canadian Securities Exchange approval.

Correction – Press Release BIOMARK ANNOUNCES PRIVATE PLACMENT Nov 2019

BioMark Signs Letter of Intent for Licensing Relationship for Clinical Validation and Development

Vancouver, British Columbia – (November 19th, 2019) – BioMark Diagnostics Inc. (“BioMark”) (CSE: BUX) (FSE: 20B) (OTCMKTS: BMKDF) is pleased to announce that it has signed a Letter of Intent (LOI) with a Chinese company named GuangDong Longhu (Longhu) related to an anticipated licensing relationship. BioMark has been in discussions with Longhu and its management group for the past 12 months. BioMark management team travelled to Longhu’s facilities to explore the technical, scientific, financial and medical infrastructure that Longhu can provide to BioMark. BioMark obtained due diligence support by Canadian federal and provincial international trade offices.


Both parties have agreed to proceed with clinical validation and development of BioMark’s latest FDA approved drug agent while incorporating a new metabolomic quantification technique. The LOI will be replaced with a definitive license agreement, but the general terms are an initial non-refundable payment by Longhu to BioMark, an equity investment into BioMark and milestone driven payments. The expected license agreement will be based on the results of clinical trials that are conservatively estimated to last one and a half to two years. Current field of use will be for lung cancer and will be expanded to other cancers upon consensual agreement and outcome of the results.


“We are excited to be involved with Longhu, which is well capitalized, has excellent clinical lab   expertise and wide medical community support. All the costs associated with this large-scale clinical trial (300 -350 participants), study registration, regulatory submission and assay optimization will be borne by Longhu. All protocols and consent forms will be supported by Ethics approval from participating clinical sites and designed under Health Canada guidelines. Apart from securing capital, BioMark will be utilizing a new FDA approved agent that was recently granted patent status along with modified quantification technology. This is an important inflexion point for our company as we gain market momentum. We look forward to working with Longhu and making our test available in the Chinese market” says Rashid Bux, CEO and President of BioMark.


Overview at the potential lung cancer market in China


China is in the midst of a lung cancer epidemic on an unprecedented scale. In 2015, there were an estimated 733,000 new lung cancer cases (17% of total cancer incidence) and 610,000 deaths (21.7% of total cancer mortality) in China. Lung cancer is the most commonly diagnosed cancer and the leading cause of cancer mortality in China. As lung cancer incidence and mortality have been decreasing in most high-income countries, lung cancer incidence and mortality rates in China have been steadily increasing since 1990. The most substantial factor driving recent lung cancer trends in China is tobacco smoke exposure. China has the largest smoking population in the world, with around 316 million adult smokers, and accounts for nearly 30% of smokers and 40% of tobacco consumption worldwide1.


Other risk factors that could increase lung cancer incidence in China include air pollution and occupational exposure. As a result of the acceleration of urbanization and industrial progress, the side effects of air pollution are becoming increasingly severe. Air pollution has recently been classified as the primary carcinogen. The International Agency for Research on Cancer has classified occupational exposure as a group 1 lung carcinogen. The main occupational factors include asbestos and dust.2


1Translational Lung Cancer Res 2019;8(Suppl 1): S21-S30 Tobacco and the lung cancer epidemic in China by Mark Parascandola, Lin Xiao

2 Thoracic Cancer. 2019 Jan; 10(1): 3–7. Epidemiology of lung cancer in China by Maomao Cao and Wanqing Chen

BioMark Signs Letter of Intent


Vancouver, British Columbia – (August 27th, 2019) – BioMark Diagnostics Inc. (“BioMark”) (CSE: BUX) (FSE: 20B) (OTCMKTS: BMKDF) is pleased to announce that the article “Predictive value and clinical significance of increased SSAT-1 activity in healthy adults” has been published in the peer-reviewed journal Future Science OA.


Rashid Ahmed, President and CEO, says, “This is our latest trilogy SSAT-1(Spermidine/spermine N1-acetyltransferase ) publication and we would like to acknowledge the contributions made by a dedicated team of clinicians, scientists and researchers. This publication provides additional scientific validation and evidence that one of our technology platforms (SSAT1 assay) has important clinical applications in the cancer diagnostic space. In our previous clinical studies, we observed that some healthy volunteers (“outliers”) had, higher than expected acetylated amantadine (AA) concentration. This was intriguing and we subsequently conducted detailed clinical assessments. Analysis of the ‘outliers’ observed in previous studies using the amantadine test revealed that a large number were at risk or developed cancer, suggesting that the test can predict the occurrence of cancer. Monitoring of urinary AA concentration combined with clinical and hematological characteristics could be established as a useful tool for purposes of screening and follow-up for cancer in high-risk populations. Our findings in ‘outliers’ support usefulness of amantadine assay as a screening or surveillance test in populations considered at high risk for developing cancer. It is also possible that this test could be used for monitoring patients after curative surgical or chemoradiation therapy to assess eradication of the tumor. Also, in follow-up, it could possibly detect proliferation of new cancer cells (relapse)”.


“We are on track to publish additional peer reviewed papers and present abstracts or posters in the near term on significant discoveries that we have strategically invested resources over the past few years.” says Rashid.


The paper is available through open access at https://www.future- and on BioMark encourages subscription to Future Science for individuals and institutions interested in keeping abreast of new developments in biotechnology and medicine.


About Future Science OA

Launched in March 2015, Future Science OA is the inaugural gold open access journal from Future Science Group. It publishes articles covering research of application to human health and utilizes a CC-BY license. Future Science OA embraces the importance of publishing all good-quality research with the potential to further the progress of medical science. Negative and early-phase research will be considered. The journal also features review articles, editorials and perspectives, providing readers with a leading source of commentary and analysis.

About Future Science Group

Founded in 2001, Future Science Group (FSG) is a progressive publisher focused on breakthrough medical, biotechnological, and scientific research. FSG’s portfolio includes two imprints, Future Science and Future Medicine. Both publish eBooks and journals. In addition to this core publishing business FSG develops specialist eCommunities. Key titles and sites include Bioanalysis Zone, Epigenomics, Nanomedicine and the award-winning Regenerative Medicine. The aim of FSG is to service the advancement of clinical practice and drug research by enhancing the efficiency of communications among clinicians, researchers and decision-makers, and by providing innovative solutions to their information needs. This is achieved through a customer-centric approach, use of new technologies, products that deliver value-for-money and uncompromisingly high standards.

For all queries, contact Laura Dormer email to:>



Vancouver, British Columbia – (August 19th, 2019) – BioMark Diagnostics Inc. (“BioMark”) (CSE: BUX) (FSE: 20B) (OTCMKTS: BMKDF) is pleased to announce that the article “Liquid Biopsy in Lung Cancer Screening: The Contribution of Metabolomics. Results of A Pilot Study” will be on cover of Cancers.


Rashid Ahmed, President and CEO, says, “This latest paper that was published a few days ago paper has been selected by the editors of the journal as the cover of the forthcoming issue. The issue cover will be displayed on the issue page:, and promoted in the issue released notification which will be sent to the journal subscribers together with the table of contents. I would like to thank and acknowledge the team for their excellent contribution that resulted in recognition of this manuscript.”


The paper is available through : and or at


About Cancers

Cancers (ISSN 2072-6694) is an international, peer-reviewed open access journal on oncology. It publishes article types including Research Papers, Reviews, Editorials, Communications, etc. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. The full experimental details must be provided so that the results can be reproduced.

There is, in addition, a unique feature of this journal: we accept studies showing meaningful but negative results. While there are many journals that focus on cancer studies, none of them actively accepts negative results. As a result, most negative data end up not being in the public domain even if the data were meaningfully negative and the study well designed. By accepting those negative results, our journal encourages scientists to share those data so that they would not need to repeat the experiments that somebody else has already done.


Scope of Journal

We publish high-quality articles including basic, translational, and clinical studies on all tumor types (